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When xylazine is taken in combination with opioids such as fentanyl, it increases the risk of a life-threatening overdose. Most overdose deaths related to both xylazine and fentanyl also involve additional substances, such as cocaine, benzodiazepines, alcohol, methadone, and prescription opioids.

Responding to an overdose ›

Xylazine Test Strips 

Testing drugs before using them can help reduce the risks of xylazine and overdose. 

Xylazine Test Strips ›

Sources: NIDA ,CDC, National Harm Reduction Coalition